How do we implement ANNEXXa-I into our Clinical Practice?

November 30, 2023
For acute care physicians, anticoagulated patients presenting with intracranial hemorrhage (ICH) is an incredibly challenging clinical scenario. ANNEXa-I is a randomized, controlled, clinical trial which provides clinicians with important information on appropriate reversal of anticoagualtion to optimally care for these patients.
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Real World Evidence for Management of Severe Bleeding in the Anticoagulated Patient: Impact of Specific Reversal Therapy for Intracranial Hemorrhage and Gastrointestinal Bleeding

July 28, 2023

Real World studies can provide the foundational support necessary for clinicians to effectively manage anticoagulated patients with severe, often life-threatening intracranial and gastrointestinal bleeding. While randomized controlled clinical trials have provided the initial data necessary for appropriate use of reversal agents such as andexanet alfa for Factor Xa associated bleeding, broader studies enrolling thousands of patients, many with significant co-morbidities, are extremely valuable to clinicians. New information regarding the randomized controlled trial ANEXXA-I, which was halted due to andexanet alfa efficacy, provides additional information supporting reversal therapy for severe bleeding.

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The Role of Real World Evidence in Driving Clinical Care for Anticoagulated Patients with Life-Threatening Bleeding

March 31, 2023
Experts in Emergency Medicine, Pharmacy, and Neurocritical Care describe the impact of real world evidence on the care of life-threatening bleeding in the anticoagulated patient. While clinical trial data remain the standard for clinicians, real world data provide important additional information on the use of a particular Repletion or Reversal therapy for these patients.
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What Are the Barriers to Success When Implementing Care Pathways for ICH Patients?

July 12, 2022

ICH remains deadly and pathways matter but they aren't always what we need and barriers can be overcome with knowledge.

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How Do We Coordinate Care Within Our Hospitals To Improve Outcomes in Hemorrhagic Stroke Patients?

July 5, 2022
Coordinating the necessary care for hemorrhagic patients is complicated- learn the ropes from experts on the UC Stroke Team. "Smoother, faster better" is the name of the game.
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Mar 11

The New Standards for Prehospital Stroke Patient Destinations; the Dawn of a New Era in EMS

BryanAdminTest posted on 3/11/2021

Moderator: Jordan Bonomo, MD, FCCM, FNCS
Other Participants: Christopher T. Richards, MD, MS, FAEMS, FACEP

The destination for prehospital patients with suspected stroke has been controversial for many years. Should they be taken to the closest ED, the closest stroke ready hospital, or the closest comprehensive stroke center? Does rural, suburban, or urban location matter when selecting a receiving institution? The new AHA white paper addresses this and more.

Timed with the release of a new white paper by the AHA, this podcast with prehospital stroke expert Dr. Christopher Richards explores the best practices and new recommendations released on 3/11/21. Controversial topics of destination and timing of transport are addressed and a call to unify practices nationally in the face of compelling evidence are the foundations of the white paper and discussion with Dr. Richards, who co-authored the white paper. Listen in for a discussion that may change your understanding of prehospital stroke transport and the future of stroke EMS.   

To read the full article visit the AHA Journals website.

Podcast Duration13:03
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