Real World Evidence for Management of Severe Bleeding in the Anticoagulated Patient: Impact of Specific Reversal Therapy for Intracranial Hemorrhage and Gastrointestinal Bleeding

July 28, 2023

Real World studies can provide the foundational support necessary for clinicians to effectively manage anticoagulated patients with severe, often life-threatening intracranial and gastrointestinal bleeding. While randomized controlled clinical trials have provided the initial data necessary for appropriate use of reversal agents such as andexanet alfa for Factor Xa associated bleeding, broader studies enrolling thousands of patients, many with significant co-morbidities, are extremely valuable to clinicians. New information regarding the randomized controlled trial ANEXXA-I, which was halted due to andexanet alfa efficacy, provides additional information supporting reversal therapy for severe bleeding.

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How Do We Coordinate Care Within Our Hospitals To Improve Outcomes in Hemorrhagic Stroke Patients?

July 5, 2022
Coordinating the necessary care for hemorrhagic patients is complicated- learn the ropes from experts on the UC Stroke Team. "Smoother, faster better" is the name of the game.
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Are We Prepared To Manage Anticoagulated ICH Patients or Should We Direct Them Elsewhere?

June 28, 2022
How and where to treat ICH patients- politics, reversal agents, and science all in one podcast!
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MRI In Acute Stroke: Promises and Pitfalls

April 12, 2022
MRI imagining is becoming more available in acute settings; understanding MRI in stroke is critical to staying ahead of the curve.
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How Do You Operationalize the Use of the ASPECTS Score and Is It the Poor Man’s CTP?

April 5, 2022
The ASPECTS score has become more widespread in use with the increase in availability of endovascular therapy. This podcast is a must if you care for acute stroke patients. This is an absolute "must-know" topic for anyone who looks at head CT images in strokes.
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